The ambitious Phase II upgrades of the ATLAS and CMS detectors, necessary to deal with the tenfold increase in data to be delivered by the High-Luminosity LHC, are pushing detector technologies to new heights. This issue also looks back on the discovery of the W and Z bosons and on the origins of the SESAME light source, showcases the latest applications of accelerator technology in radiotherapy and aviation, and reports on the latest results from LHCb concerning the flavour anomalies.